Proteotranscriptomic Measurements of E6-Associated Protein (E6AP) Targets in DU145 Prostate Cancer Cells
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چکیده
منابع مشابه
Activating Transcription Factor 3 (ATF3) Activates p53 in Cervical Cancer Cells by Preventing E6-associated Protein (E6AP) fro
Genomic integration of human papillomavirus (HPV) DNA accounts for more than 90% of cervical cancers. High-risk genital HPVs encode E6 proteins that can interact with a cellular ubiquitin ligase E6-associated protein (E6AP) and target the tumor suppressor p53 for ubiquitin-mediated proteolysis. Currently, how this critical event is regulated is largely unknown. Here we report that activating tr...
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ژورنال
عنوان ژورنال: Molecular & Cellular Proteomics
سال: 2018
ISSN: 1535-9476
DOI: 10.1074/mcp.ra117.000504